Ali GIO Health and Healing Course , Part Two – Strong Scientific Claims Require Strong Scientific Evidence


 

Majid Ali, M.D.

140 West End Avenue, Suite 1-H, New York, NY 10023

212-873-2444

344 Prospect Avenue, Suite 3-C, Hackensack, NJ. 07610

201-996-0027 


 

The central claim of Ali GIO Self-Healing to Self-Empowerment to Self-Healing (GIO Health and Healing model) is that the three primary mechanisms of cellular injury in all chronic diseases are:

  1. Disrupted Molecular Biology of Oxygen and perverted oxygen signaling

  2. Disrupted Insulin Homeostasis and perverted insulin signaling (insulin toxicity)

  3. Disrupted gut ecology and perverted degrees of gut fermentation (increased gut burden of gut flora.


The above three are serious scientific claims that I make in Ali GIO Healing and form the basis of my next three scientific claims: 

  1. No treatment plans for healing any chronic disease can be considered complete unless all disrupted oxygen signaling is restored to normal oxygen signaling.

  2. No treatment plans for healing any chronic disease can be considered complete unless all disrupted insulin signaling is restored to normal oxygen signaling.

  3. No treatment plans for healing any chronic disease can be considered complete unless all disrupted patterns of gut ecology and gut microbiome are restored to normal gut ecology and gut microbiome.


Lines of Evidence

  1. Scientific Basis of the Criteria for Diagnosis, Treatment, and Outcome

  2. Scientific Rationale of the Criteria for Diagnosis, Treatment, and Outcome

  3. Clinical Data at the Time of Diagnosis 

  4. Laboratory Data at the Time of Diagnosis

  5. Clinical Data at the End of the Study Period 

  6. Laboratory Data at the the Time of Diagnosis

  7.  Laboratory Data at the End of the Study Period

  8. Statistical Analysis of Cumulated Data

  9. Long-Term Followup Stats


Seven Parts of Health and Healing Course

 

  1. Ali GIO Health and Healing Course Introduction – Three Root Problems, Three Sets of Solutions
  2. Ali GIO Health and Healing Course, Part One – Self-learning to Self-Empowering to Self-Healing Chronic Disease
  3. Ali GIO Health and Healing Course, Part Two –Strong Scientific Claims Require Strong Scientific Evidence
  4. Ali GIO Health and Healing Course, Part Three – Energy Thinking for Energy Healing
  5. Ali GIO Health and Healing Course, Part Four – Safety First, Acute and Chronic Diseases
  6. Ali GIO Health and Healing Course, Part Five – Top Seven for Gut, Oxygen, and Insulin
  7. Ali GIO Health and Healing Course, Part Six – The Gut-Liver-Brain Connections
  8. Ali GIO Health Healing Course,         Part Seven – The Spiritual Dimension             Course Study Materials

ALI GIO Health and Healing Library

of Published Articles and Book

  1. Ali M. Oxidative regression to primordial cellular ecology. J Integrative Medicine 1998; 2:4-55.
  2. Ali M. Bradford R, Ali O, et al. Immunostaining of Candida organisms in peripheral blood blood smears (abstract) 1995, American Academy of Otolaryngic Allergy, Spring Meeting, Palm Desert, CA.
  3. Ali M. Ramanarayanan MP:  A computerized micro-ELISA assay for allergen-specific IgE antibodies.  Am J Clin Pathol, 81:591-601, 1984.
  4. Ali M. Ramanarayanan MP, Nalebuff DJ, Fadal RG, Willoughby JW:  Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: effect of specific immunotherapy.  Am J Clin Pathol, 80:290-299, 1983.
  5. Ali M. Respiratory-to-fermentative shift in immune-inflammatory disorders with energy deficit. Townsend Letter. 2004; 253;64-65.
  6. Ali M. Krebs cycle impairment – molecular biology of  oxygen. communication. Communication E-published. Nature. 2014;515:431. 
  7. Ali M. Ali O. Oxidative coagulopathy in fibromyalgia and chronic fatigue syndrome. Am J Clin Pathol  1999; 112:566-7.Ali M. Krebs cycle impairment – molecular biology of  oxygen. communication. Communication E-published. Nature. 2014;515:431. 
  8. Ali M. Oxygen and Aging. . (2nd ed.) New York, Canary 21 Press. 2004.
  9. Ali M. Spontaneity of oxidation in Nature and Aging. Monograph). Teaneck, New Jersey, U.S.A. 1983.
  10. Ali M. Hurt human habitat and energy deficit—Healing Through Restoration of Krebs cycle chemistry. Townsend Letter-The examiner of Alternative Medicine. 2006; 279:112-115.
  11. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  12. Ali M. The Principles and Practice of Integrative Medicine Volume  IV: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  13. Ali M. Altered States of Bowel Ecology. Monograph. Teaneck, New Jersey.1980.
  14. Ali M. The dysox model of aging.  Townsend Letter for Doctors. and Patients.2005;269:130-134.
  15. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.
  16. Ali M. Obesity is cellular oxygen defunction state. Aging Healthfully Healthfully.  2004;5:2-19.
  17. Ali M. The oxidative-dysoxygenative perspective of allergic disorders. J Integrative Med. 2000; 4:1-17.
  18. Ali M. Beyond insulin resistance and syndrome X: The oxidative-dysoxygenative insulin dysfunction (ODID) model. J Capital University of Integrative Medicine. 2001;1:101-141.
  19. Ali M. The Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.
  20. Ali M. Oxygen, Insulin Toxicity, Inflammation, and  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the  Clinical Benefits of Chelation – Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010. 
  21. Ali M. Epidemic of Dysoxygenosis and the Metabolic Syndrome. In: The Principles and Practice of Integrative Medicine. Volume 5. Pp 246-256. Canary 21 Press. New York. 2005.
  22. Ali M. Insulin: the life span hormone for healthful aging. Townsend Letter. The Examiner of Alternative Medicine . 2018;416:54-59.
  23. Ali M. Death begins in the colon. Ali Academy.  http://aliacademy.org/problems_of_the_gut.htm
  24. Ali M. As roots are to roses, so the bowel to the brain. Diseaases begin in the fermenting colon.  Ali Academy.http://aliacademy.org/problems_of_the_gut.htm
  25. ‘Ali M. Ali M. Seed, Feed, and Weed Plan for Restoring Gut Flora   and Metabolic Health. Communication e-published in Nature. 2016;535:56-64.
  26. Chouchani ET, Pell VR, Guade E, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature.2014;515:431-435.
  27. Ali M. The agony and death of a cell. In: Syllabus of the Instruction Course of the American Academy of Environmental Medicine. Denver, Colorado, 1985.
  28. Ali M.The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  29. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  30. Ali M. The Principles and Practice of Integrative Medicine Volume  XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press. 
  31. Ali M. Petrochemical Illness and philic-phobic dysequilibrium in the Gulf of Mexico. Townsend Letter-The examiner of Alternative Medicine. 2010;76:79. November 2010.
  32. Ali M. Oxyphilic Nature Ali M. Fungal Infections and Oxyphile-Oxyphobic Conflicts. Communication e-published Nature. 2017.
  33. Ali M. The dysox model of renal insufficieny and improved renal function with oxystatic therapies. Townsend Letter for Doctors and Patients.2005;267:101-108.
  34. Ali M. Fischer S, Juco J, et al. The dysox model of coronay artery disease. Townsend Letter for Doctors and Patients. 2006;270/71:110-112.
  35. Ali M. The ADHD-Autism-Oxygen Connection: The Larger-Head-Smaller-Brain Scenario. Townsend Letter-The examiner of Alternative Medicine. April, 2008. http://www.townsendletter.com.
  36. Ali M. Oxygen model of Alzheimer’s disease. In . Oxygen and Aging. (2nd ed.) New York, Canary 21 Press. 2004.
  37. Ali M. Darwin Moms, Nursing Milk, and Antibiotic Resistance. In: Nature; 2016. 533:212.
  38. Progenitor stem cell progression model of autism (PSP Autism model). spectrum WordPress. 2016.
  39. Ali M.  Osteocrin, making connections, and autism. Communication e-published. Nature. 2016;539:242.
  40. Ali M. Chronic disease is evolution in reverse. Communication e-published. Nature. 2016. 530:268. 
  41. Ali M. The Principles and Practice of Integrative Medicine Volume I: Nature’s Preoccupation With Complementarity and Contrariety. New York. Canary 21 Press. 1998. 2nd edition  2005.
  42. Ali M. The Principles and Practice of Integrative Medicine Volume  II: The History and Philosphy of Integrative Medicine. 2001.  New York. Canary 21 Press. 1998. 2nd edition  2006.
  1. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999
  2. Ali M. The Principles and Practice of Integrative Medicine Volume  IV: Integrative Immunology and Allergy: The Oxidative-Dysoxygenative Perspective.  New York. Canary 21 Press. 1998. 2nd edition  2005.
  3. Ali M. The Principles and Practice of Integrative Medicine Volume  V: Integrative Nutritional Medicine: Nutrition Seen Through the Prism of Oxygen Homeostasis.  New York. Canary 21 Press. 1999. 2nd edition  2005.
  4. Ali M. Oxidative cell membrane disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
  5. Ali M. Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;3:11-16.
  6. Ali M:  Molecular basis for the use of antioxidants to regulate plasma membrane dynamics in allergic disorders.  abstracts, Annual Meeting of the American Academy of Otolaryngic Allergy, page 30, 199l.
  7. Ali M: Darwin, fatigue, and fibromyalgia.J Integrative Medicine 1999;3:5-10.
  8. Xu G, Buyun, SL, Buyun. Corrected prevalence of autism spectrum disorder among US children and adolescent. JAMA. 2018;319:505.
  9. He L, Si G, Huang J, et al. Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel. Nature. 2018;555:103-106.
  10. intestinal stem cell xxxxxxxxx xxxxxx / https://alihealing.org/2018/10/02/what-might-autism-teach-about-alzheimers-disease-ad-what-might-ad-teach-about-autism/

 

  1. Noctor SC, Martinez-Cerdeno V, Kriegstein AR. Contribution of intermediate progenitor cells to cortical histogenesis. Arch. Neurol. 2007;64:639-642.
  2. Seaberg RM, Van Der Kooy D. Stem and Progenitor cells. The premature desertion of rigorous definitions. Trends in Neurosciences. 2003;26:125-131.

56.Toriumi K, Mouri A, Narusawa S, et al. Prenatal NMDA Receptor Antagonism Impaired Proliferation of Neuronal Progenitor, Leading to Fewer Glutamatergic Neurons in the Prefrontal Cortex. Neuropsychopharmacology.2012;37: 1387-139./

  1. 57. Krakowiak P, Walker CK, Bremer AA, et al. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics2012; 129(5): e1121–e1128.
  2. Bilbo SD, Tsang V. Enduring consequences of maternal obesity for brain inflammation and behavior of offspring. FASEB J 2010; 24(6): 2104–2115.
  3. Catalano P. The impact of gestational diabetes and maternal obesity on the mother and her offspring. J Dev Orig Health Dis2010; 1(04): 208–215.
  4. Van Lieshout R, Taylor V, Boyle M. Pre‐pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev 2011; 12(5): e548–e559.
  5. Kosidou K,Kalman C, Gardner RM. Maternal Polycystic ovary syndrome and the risk of Autism spectrum disorders in the offspring. A population-based nationwide study in Sweden. Molecular Psychiatry.21:1441-144b.
  6. Cheslack-Postava K, Fallin MD. Beta adrenergic receptor gene variant and risk of autism in the AGRE cohort. Molecular Psychiatry. 2007;12:283-81.
  7. 63. Yazawa M, et al.Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 471, 230–234 (2011).
  8. Sugimura R, Jha DK, Han Areum et al.  Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017;545;432-38.
  9. Lancaster, M. A. et al.Cerebral organoids model human brain development and microcephaly. Nature.2013;501, 373–379.
  10. Ataman B, Boulting G, Harmin DA, et al. Evolution of Osteocrin as an activity-regulated factor in the primate brain. Nature.  2016; 539: 242-247.
  11. Canter RG,Penney J, Tsai L-H. The road to restoring neural circuits for the treatment of Alzheimer’s disease. Nature. 2016;539:187-196.
  12. Mardinly, A. R. et al.Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons. Nature. 2016;531, 371–375.
  13. Quadrato G, Nguyen T, Macosko EZ, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53.
  14. Birey F. Anderson J, Makinson CD. Et al.Assembly of functionally integrated human forebrain spheroids. Nature.2017;545:54-59.

71.Sweatt D, Layered-up regulation in the development developing brain.  Communication e-published.Nature. 2017;551:448-9. 

  1. Kapp FG, Perlin JR, Hagedorn EJ, et al. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. 2018;558:445-448.
  2. Lin G, Xu N, Xi, Paracrine signaling controls self-renewal of Drosophila intestinal stem cells.. Nature.2008;455.
  3. Ali M. Epigenetic and Clinical Implications of Neural Spheroids and Organoids In Treating Autism.. Communication. E-Published. Nature. 2017;545:54-59. 
  4. Ali M Unpacking Brain Organoids and Spheroids for Delineating the Impeded Progenitor Cell Progression Model of the Autism Spectrum Disorder. Communicaion. E-Published. Nature. 2017; 545:48-53.
  5. Ali M.  Genetics and Comorbidities of the Autism Spectrum disorder. Communicaion. E-PublishedNature. 2017;543:507-512.
  6. Ali M.  Integration of Empirical Measures for Brain  Rejuvenation. Communicaion. E-Published.Nature. 2016;539:187.
  7. Ali M. Osteocrin, Making Connections, and Autism.  Communication e-published. Nature. 2016;539:242.
  8. Ali M.  Genetics and Comorbidities of the Autism Spectrum

     disorder. Communicaion. E-Published Nature. 2017;543:507-512.

  1. Ali M.  Integration of Empirical Measures for Brain  Rejuvenation. Communication e-published. Nature. 2016;539:187.
  2. Ali M.Tribal Brain Model and Autism. Communication e-published. Nature. 2018;554:364-367.
  3. Ali M. Enteroendocrine Stem cells and Two Dimensions Enteroendocrine Dimension of the Autism Spectrum Disorder. Nature. 2018;555:103-106.
  4. Ali M. Epigenetic and Clinical Implications of Neural Spheroids and Organoids for integrative Management of Autism. Communication e-published in Nature. Nature.2017;545:54-59.
  5. Ali M. Hypothalamic Influences on Metabolism, Feeding, and Insulin. Nature. 2016;531:647-650.
  6. Ali  M. Irritable Bowel Syndrome and Seed,Feed, and Weed Approach. Communication e-published. Nature.  2016;533.
  7. Ali M. Darwin Moms , Nursing Milk, and Antibiotic Resistance. Communication e-published. Nature.2017;533:212.
  8. Ali M.Maternal Gut Microbes, Immune Connections, and Autism Circuits. Comment. E-Published. Nature. 2018; 549:528–532 & . 482-487.
  9. Ali M. Women-Like Men and Men-Like Women . Nature 533:206.
  10. Ali M.  Menstruating Mice and Human Reproductive Health. Nature. 2016.June.
  11. Ali M. 30. Workable Simplicity for Coping With Complexity of Diabetes. Nature.2016;534: 447
  12. Ali M. Reversing Diabetes – Acetate Mediates Metabolic   Syndrome. Nature.2016;534: 213

93.Ali M. Recognized Empirtical Benefits of Methylation – What Next? Communication e-published.Nature. 2016;369:373.

  1. Ali M. Darkfield Ali M. The Crab, Oxygen and Cancer. Volume I: The Dysox Model of Cancer.  2007.  New York, Canary 21 Press. Pages 114-116.
  2. Ali M. Cell Membrane Dysregulation. Syllabus. American Academy of Environmental Medicine. 1988. 13th Instructional Course. Cleveland, Ohio. pp 109-137.
  3. https://www.cdc.gov/mold/stachy.htm.
  4. Bitnun A, Nosal RM. Stachybotrys chartarum (atra)contamination of the indoor environment: Health implications. Paediatr Child Health. 1999;4:125-129.
  5. Shaw, W., et. al. Increased Urinary Excretion of Analogs of Krebs Cycle Metabolites and Arabinose in Two Brothers with Autistic Features. Clin Chem 41:1094-1104, 1995. 99. Shaw, W., et. al. Assessment of antifungal drug therapy in autism by measurement of suspected microbial metabolites in urine with GC/MS. Clinical Practice of Alternative Medicine: 15-26.
  6. https://alihealing.org/2018/10/02/what-might-autism-teach-about-alzheimers-disease-ad-what-might-ad-teach-about-autism/
  7. Ali M. Succinate Retention. In: Chouchani ET, Victoria R. Pell VR, Edoardo Gaude E, et. al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 2014;515:431–435.
  8. Ali M. Succinate Retention: The Core Krebs Dysfunction in Immune-Inflammatory Disorders. Townsend Letter. 2015;388:84-85.
  9. Ali M: Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;3:11-16.
  10. Climatic Chaos –  The primacy of oxygen issues over carbon issues. Part I. Townsend Letter-The examiner of Alternative Medicine. 2008;299:125-132.
  11. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  12. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  13. Ali M. Epidemic of Dysoxygenosis and the Metabolic Syndrome. In: The Principles and Practice of Integrative Medicine. Volume 5. Pp 246-256. Canary 21 Press. New York. 2005.
  14. Ali M. Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.
  15. Ali Plan for Reversing Diabetes. New York, Canary 21 Press. Aging Healthfully Book 2011.
  16. Ali M. Oxygen, Insulin Toxicity, Inflammation, and  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.
  17. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  18. Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the  Clinical Benefits of Chelation – Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010. 
  19. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  20. Ali M. Oxidative Cell Membrane Disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
  21. Kahn SE, 1, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444, 840-846.
  22. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116 :1793B1801.
  23. Shulman G. Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease. N Engl J Med. 2014; 371:1131‑
  24. International Diabetes Federation. Diabetes Atlas. 2016. Seventh edition. diabetesatlas.org.
  25. Sako, Y. & Grill, V. E. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology127, 1580–1589 (1990).|
  26. Kahn, S. E., Bergman, R. N., Schwartz, M. W., Taborsky, G. J. & Porte, D. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans.  J. Physiol.1992;262: E518–E523.
  27. Ali M. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  28. Ali M, Braun EV, Fayemi AO:  Pathology.  7th ed.  New York, Med Exam, 1980,370 pp.
  29. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.Aging
  30. Ali M, Ramanarayanan MP, Nalebuff DJ, Fadal RG, Willoughby JW:  Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: effect of specific immunotherapy.  Am J Clin Pathol, 80:290-299, 1983.
  31. Ali M. Spontaneity of Oxidation in Nature and Aging,  (monograph). Teaneck, NJ, 1983.
  32. Ali M, Ramanarayanan MP:  A computerized micro-ELISA assay for allergen-specific IgE antibodies.  Am J Clin Pathol, 81:591-601, 1984.
  33. Ali M.   Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  34. Ali M. Altered States of Biology Ecology. (monograph). Teaneck, NJ, 1980.
  35. Murphy KG, Bloom SR. Gut hormones and the regulation of energy bhomeostasis. 2006;444:854-859.

  36. Ali M. Dysox Model of Cancer Cancer
  37. Philosophy and Science of holism in healing. APPNA Journal. 2015.
  38. Ali M. Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  39. Ali M. Molecular Basis of Autism and Dysuatonomia – The Impeded Progenitor Cell Progression (IPCP) model of ASD and Dysautonomia. Townsend Letterfor Doctors and Patients. 2017 (In press)
  40. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  41. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  42. Ali M. The Principles and Practice of Integrative Medicine Volume  XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press. 
  43. Insulin Laboratory Ranges. http://alidiabetes.org/2016/02/25/insulin-laboratory-ranges/
  44. Ali Importance of Subtyping Diabetes Type 2 Into Diabetes Type 2A and Diabetes Type 2B. Townsend Letter-The Examiner of Alternative Medicine. 2014; 369:56-58.
  45. Ali M. Dasoju S, Karim N, Amin J, Chaudary D. Study of Responses to Carbohydrates and Non-carbohydrate Challenges In Insulin-Based Care of Metabolic Disorders. Townsend Letter-The Examiner of Alternative Medicine. 2016; 391:48-51.
  46. Ali M. Integrative Cardiology and Chelation Therapies. The Principles and Practice of Integrative Medicine. Vol VI. . (2005) New York. Institute of Integrative Medicine Press.
  47. Fontoura P. Harnessing Emerging Science for Unmet Needs patient needs. In: Sponsor Feature. Nature. 2016;491, Preceding page S1.
  48. Wall DP, Esteban FJ, Deluca TF et al. Comparative analysis of neurological disorders focuses genome-wide search for autism genes. Genomics. 2008;93(2):120–9.

ALI GIO HEALING VIDEO LIBRARY

The left side panel of all parts of ALI GIO Healing presents in alphabetical order a large library of the author’s videos on diverse subjects covered in the series of articles. Two video links are included below as examples.

Redaers will find this series very informative an duseful.

END END

The central claim of Ali GIO model is that the three primary mechanisms of cellular injury in all chronic diseases are:

  1. Disrupted Molecular Biology of Oxygen and perverted oxygen signaling

  2. Disrupted Insulin Homeostasis and perverted insulin signaling (insulin toxicity)

  3. Disrupted gut ecology and perverted degrees of gut fermentation (increased gut burden of gut flora.


 

The above three are serious scientific claims that I make in Ali GIO Healing and form the basis of my next three scientific claims: 

  1. No treatment plans for healing any chronic disease can be considered complete unless all disrupted oxygen signaling is restored to normal oxygen signaling.

  2. No treatment plans for healing any chronic disease can be considered complete unless all disrupted insulin signaling is restored to normal oxygen signaling.

  3. No treatment plans for healing any chronic disease can be considered complete unless all disrupted patterns of gut ecology and gut microbiome are restored to normal gut ecology and gut microbiome.


ALI GIO Library of Published Articles and Book

  1. Ali M. Oxidative regression to primordial cellular ecology. J Integrative Medicine 1998; 2:4-55.
  2. Ali M. Bradford R, Ali O, et al. Immunostaining of Candida organisms in peripheral blood blood smears (abstract) 1995, American Academy of Otolaryngic Allergy, Spring Meeting, Palm Desert, CA.
  3. Ali M. Ramanarayanan MP:  A computerized micro-ELISA assay for allergen-specific IgE antibodies.  Am J Clin Pathol, 81:591-601, 1984.
  4. Ali M. Ramanarayanan MP, Nalebuff DJ, Fadal RG, Willoughby JW:  Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: effect of specific immunotherapy.  Am J Clin Pathol, 80:290-299, 1983.
  5. Ali M. Respiratory-to-fermentative shift in immune-inflammatory disorders with energy deficit. Townsend Letter. 2004; 253;64-65.
  6. Ali M. Krebs cycle impairment – molecular biology of  oxygen. communication. Communication E-published. Nature. 2014;515:431. 
  7. Ali M. Ali O. Oxidative coagulopathy in fibromyalgia and chronic fatigue syndrome. Am J Clin Pathol  1999; 112:566-7.Ali M. Krebs cycle impairment – molecular biology of  oxygen. communication. Communication E-published. Nature. 2014;515:431. 
  8. Ali M. Oxygen and Aging. . (2nd ed.) New York, Canary 21 Press. 2004.
  9. Ali M. Spontaneity of oxidation in Nature and Aging. Monograph). Teaneck, New Jersey, U.S.A. 1983.
  10. Ali M. Hurt human habitat and energy deficit—Healing Through Restoration of Krebs cycle chemistry. Townsend Letter-The examiner of Alternative Medicine. 2006; 279:112-115.
  11. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  12. Ali M. The Principles and Practice of Integrative Medicine Volume  IV: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  13. Ali M. Altered States of Bowel Ecology. Monograph. Teaneck, New Jersey.1980.
  14. Ali M. The dysox model of aging.  Townsend Letter for Doctors. and Patients.2005;269:130-134.
  15. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.
  16. Ali M. Obesity is cellular oxygen defunction state. Aging Healthfully Healthfully.  2004;5:2-19.
  17. Ali M. The oxidative-dysoxygenative perspective of allergic disorders. J Integrative Med. 2000; 4:1-17.
  18. Ali M. Beyond insulin resistance and syndrome X: The oxidative-dysoxygenative insulin dysfunction (ODID) model. J Capital University of Integrative Medicine. 2001;1:101-141.
  19. Ali M. The Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.
  20. Ali M. Oxygen, Insulin Toxicity, Inflammation, and  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the  Clinical Benefits of Chelation – Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010. 
  21. Ali M. Epidemic of Dysoxygenosis and the Metabolic Syndrome. In: The Principles and Practice of Integrative Medicine. Volume 5. Pp 246-256. Canary 21 Press. New York. 2005.
  22. Ali M. Insulin: the life span hormone for healthful aging. Townsend Letter. The Examiner of Alternative Medicine . 2018;416:54-59.
  23. Ali M. Death begins in the colon. Ali Academy.  http://aliacademy.org/problems_of_the_gut.htm
  24. Ali M. As roots are to roses, so the bowel to the brain. Diseaases begin in the fermenting colon.  Ali Academy.http://aliacademy.org/problems_of_the_gut.htm
  25. ‘Ali M. Ali M. Seed, Feed, and Weed Plan for Restoring Gut Flora   and Metabolic Health. Communication e-published in Nature. 2016;535:56-64.
  26. Chouchani ET, Pell VR, Guade E, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature.2014;515:431-435.
  27. Ali M. The agony and death of a cell. In: Syllabus of the Instruction Course of the American Academy of Environmental Medicine. Denver, Colorado, 1985.
  28. Ali M.The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  29. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  30. Ali M. The Principles and Practice of Integrative Medicine Volume  XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press. 
  31. Ali M. Petrochemical Illness and philic-phobic dysequilibrium in the Gulf of Mexico. Townsend Letter-The examiner of Alternative Medicine. 2010;76:79. November 2010.
  32. Ali M. Oxyphilic Nature Ali M. Fungal Infections and Oxyphile-Oxyphobic Conflicts. Communication e-published Nature. 2017.
  33. Ali M. The dysox model of renal insufficieny and improved renal function with oxystatic therapies. Townsend Letter for Doctors and Patients.2005;267:101-108.
  34. Ali M. Fischer S, Juco J, et al. The dysox model of coronay artery disease. Townsend Letter for Doctors and Patients. 2006;270/71:110-112.
  35. Ali M. The ADHD-Autism-Oxygen Connection: The Larger-Head-Smaller-Brain Scenario. Townsend Letter-The examiner of Alternative Medicine. April, 2008. http://www.townsendletter.com.
  36. Ali M. Oxygen model of Alzheimer’s disease. In . Oxygen and Aging. (2nd ed.) New York, Canary 21 Press. 2004.
  37. Ali M. Darwin Moms, Nursing Milk, and Antibiotic Resistance. In: Nature; 2016. 533:212.
  38. Progenitor stem cell progression model of autism (PSP Autism model). spectrum WordPress. 2016.
  39. Ali M.  Osteocrin, making connections, and autism. Communication e-published. Nature. 2016;539:242.
  40. Ali M. Chronic disease is evolution in reverse. Communication e-published. Nature. 2016. 530:268. 
  41. Ali M. The Principles and Practice of Integrative Medicine Volume I: Nature’s Preoccupation With Complementarity and Contrariety. New York. Canary 21 Press. 1998. 2nd edition  2005.
  42. Ali M. The Principles and Practice of Integrative Medicine Volume  II: The History and Philosphy of Integrative Medicine. 2001.  New York. Canary 21 Press. 1998. 2nd edition  2006.
  1. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999
  2. Ali M. The Principles and Practice of Integrative Medicine Volume  IV: Integrative Immunology and Allergy: The Oxidative-Dysoxygenative Perspective.  New York. Canary 21 Press. 1998. 2nd edition  2005.
  3. Ali M. The Principles and Practice of Integrative Medicine Volume  V: Integrative Nutritional Medicine: Nutrition Seen Through the Prism of Oxygen Homeostasis.  New York. Canary 21 Press. 1999. 2nd edition  2005.
  4. Ali M. Oxidative cell membrane disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
  5. Ali M. Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;3:11-16.
  6. Ali M:  Molecular basis for the use of antioxidants to regulate plasma membrane dynamics in allergic disorders.  abstracts, Annual Meeting of the American Academy of Otolaryngic Allergy, page 30, 199l.
  7. Ali M: Darwin, fatigue, and fibromyalgia.J Integrative Medicine 1999;3:5-10.
  8. Xu G, Buyun, SL, Buyun. Corrected prevalence of autism spectrum disorder among US children and adolescent. JAMA. 2018;319:505.
  9. He L, Si G, Huang J, et al. Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel. Nature. 2018;555:103-106.
  10. intestinal stem cell xxxxxxxxx xxxxxx / https://alihealing.org/2018/10/02/what-might-autism-teach-about-alzheimers-disease-ad-what-might-ad-teach-about-autism/

 

  1. Noctor SC, Martinez-Cerdeno V, Kriegstein AR. Contribution of intermediate progenitor cells to cortical histogenesis. Arch. Neurol. 2007;64:639-642.
  2. Seaberg RM, Van Der Kooy D. Stem and Progenitor cells. The premature desertion of rigorous definitions. Trends in Neurosciences. 2003;26:125-131.

56.Toriumi K, Mouri A, Narusawa S, et al. Prenatal NMDA Receptor Antagonism Impaired Proliferation of Neuronal Progenitor, Leading to Fewer Glutamatergic Neurons in the Prefrontal Cortex. Neuropsychopharmacology.2012;37: 1387-139./

  1. 57. Krakowiak P, Walker CK, Bremer AA, et al. Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics2012; 129(5): e1121–e1128.
  2. Bilbo SD, Tsang V. Enduring consequences of maternal obesity for brain inflammation and behavior of offspring. FASEB J 2010; 24(6): 2104–2115.
  3. Catalano P. The impact of gestational diabetes and maternal obesity on the mother and her offspring. J Dev Orig Health Dis2010; 1(04): 208–215.
  4. Van Lieshout R, Taylor V, Boyle M. Pre‐pregnancy and pregnancy obesity and neurodevelopmental outcomes in offspring: a systematic review. Obes Rev 2011; 12(5): e548–e559.
  5. Kosidou K,Kalman C, Gardner RM. Maternal Polycystic ovary syndrome and the risk of Autism spectrum disorders in the offspring. A population-based nationwide study in Sweden. Molecular Psychiatry.21:1441-144b.
  6. Cheslack-Postava K, Fallin MD. Beta adrenergic receptor gene variant and risk of autism in the AGRE cohort. Molecular Psychiatry. 2007;12:283-81.
  7. 63. Yazawa M, et al.Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 471, 230–234 (2011).
  8. Sugimura R, Jha DK, Han Areum et al.  Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017;545;432-38.
  9. Lancaster, M. A. et al.Cerebral organoids model human brain development and microcephaly. Nature.2013;501, 373–379.
  10. Ataman B, Boulting G, Harmin DA, et al. Evolution of Osteocrin as an activity-regulated factor in the primate brain. Nature.  2016; 539: 242-247.
  11. Canter RG,Penney J, Tsai L-H. The road to restoring neural circuits for the treatment of Alzheimer’s disease. Nature. 2016;539:187-196.
  12. Mardinly, A. R. et al.Sensory experience regulates cortical inhibition by inducing IGF1 in VIP neurons. Nature. 2016;531, 371–375.
  13. Quadrato G, Nguyen T, Macosko EZ, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53.
  14. Birey F. Anderson J, Makinson CD. Et al.Assembly of functionally integrated human forebrain spheroids. Nature.2017;545:54-59.

71.Sweatt D, Layered-up regulation in the development developing brain.  Communication e-published.Nature. 2017;551:448-9. 

  1. Kapp FG, Perlin JR, Hagedorn EJ, et al. Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche. Nature. 2018;558:445-448.
  2. Lin G, Xu N, Xi, Paracrine signaling controls self-renewal of Drosophila intestinal stem cells.. Nature.2008;455.
  3. Ali M. Epigenetic and Clinical Implications of Neural Spheroids and Organoids In Treating Autism.. Communication. E-Published. Nature. 2017;545:54-59. 
  4. Ali M Unpacking Brain Organoids and Spheroids for Delineating the Impeded Progenitor Cell Progression Model of the Autism Spectrum Disorder. Communicaion. E-Published. Nature. 2017; 545:48-53.
  5. Ali M.  Genetics and Comorbidities of the Autism Spectrum disorder. Communicaion. E-PublishedNature. 2017;543:507-512.
  6. Ali M.  Integration of Empirical Measures for Brain  Rejuvenation. Communicaion. E-Published.Nature. 2016;539:187.
  7. Ali M. Osteocrin, Making Connections, and Autism.  Communication e-published. Nature. 2016;539:242.
  8. Ali M.  Genetics and Comorbidities of the Autism Spectrum

     disorder. Communicaion. E-Published Nature. 2017;543:507-512.

  1. Ali M.  Integration of Empirical Measures for Brain  Rejuvenation. Communication e-published. Nature. 2016;539:187.
  2. Ali M.Tribal Brain Model and Autism. Communication e-published. Nature. 2018;554:364-367.
  3. Ali M. Enteroendocrine Stem cells and Two Dimensions Enteroendocrine Dimension of the Autism Spectrum Disorder. Nature. 2018;555:103-106.
  4. Ali M. Epigenetic and Clinical Implications of Neural Spheroids and Organoids for integrative Management of Autism. Communication e-published in Nature. Nature.2017;545:54-59.
  5. Ali M. Hypothalamic Influences on Metabolism, Feeding, and Insulin. Nature. 2016;531:647-650.
  6. Ali  M. Irritable Bowel Syndrome and Seed,Feed, and Weed Approach. Communication e-published. Nature.  2016;533.
  7. Ali M. Darwin Moms , Nursing Milk, and Antibiotic Resistance. Communication e-published. Nature.2017;533:212.
  8. Ali M.Maternal Gut Microbes, Immune Connections, and Autism Circuits. Comment. E-Published. Nature. 2018; 549:528–532 & . 482-487.
  9. Ali M. Women-Like Men and Men-Like Women . Nature 533:206.
  10. Ali M.  Menstruating Mice and Human Reproductive Health. Nature. 2016.June.
  11. Ali M. 30. Workable Simplicity for Coping With Complexity of Diabetes. Nature.2016;534: 447
  12. Ali M. Reversing Diabetes – Acetate Mediates Metabolic   Syndrome. Nature.2016;534: 213

93.Ali M. Recognized Empirtical Benefits of Methylation – What Next? Communication e-published.Nature. 2016;369:373.

  1. Ali M. Darkfield Ali M. The Crab, Oxygen and Cancer. Volume I: The Dysox Model of Cancer.  2007.  New York, Canary 21 Press. Pages 114-116.
  2. Ali M. Cell Membrane Dysregulation. Syllabus. American Academy of Environmental Medicine. 1988. 13th Instructional Course. Cleveland, Ohio. pp 109-137.
  3. https://www.cdc.gov/mold/stachy.htm.
  4. Bitnun A, Nosal RM. Stachybotrys chartarum (atra)contamination of the indoor environment: Health implications. Paediatr Child Health. 1999;4:125-129.
  5. Shaw, W., et. al. Increased Urinary Excretion of Analogs of Krebs Cycle Metabolites and Arabinose in Two Brothers with Autistic Features. Clin Chem 41:1094-1104, 1995. 99. Shaw, W., et. al. Assessment of antifungal drug therapy in autism by measurement of suspected microbial metabolites in urine with GC/MS. Clinical Practice of Alternative Medicine: 15-26.
  6. / https://alihealing.org/2018/10/02/what-might-autism-teach-about-alzheimers-disease-ad-what-might-ad-teach-about-autism/
  7. Ali M. Succinate Retention. In: Chouchani ET, Victoria R. Pell VR, Edoardo Gaude E, et. al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 2014;515:431–435.
  8. Ali M. Succinate Retention: The Core Krebs Dysfunction in Immune-Inflammatory Disorders. Townsend Letter. 2015;388:84-85.
  9. Ali M: Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;3:11-16.
  10. Climatic Chaos –  The primacy of oxygen issues over carbon issues. Part I. Townsend Letter-The examiner of Alternative Medicine. 2008;299:125-132.
  11. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  12. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  13. Ali M. Epidemic of Dysoxygenosis and the Metabolic Syndrome. In: The Principles and Practice of Integrative Medicine. Volume 5. Pp 246-256. Canary 21 Press. New York. 2005.
  14. Ali M. Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.
  15. Ali Plan for Reversing Diabetes. New York, Canary 21 Press. Aging Healthfully Book 2011.
  16. Ali M. Oxygen, Insulin Toxicity, Inflammation, and  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.
  17. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  18. Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the  Clinical Benefits of Chelation – Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010. 
  19. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  20. Ali M. Oxidative Cell Membrane Disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
  21. Kahn SE, 1, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444, 840-846.
  22. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116 :1793B1801.
  23. Shulman G. Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease. N Engl J Med. 2014; 371:1131‑
  24. International Diabetes Federation. Diabetes Atlas. 2016. Seventh edition. diabetesatlas.org.
  25. Sako, Y. & Grill, V. E. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology127, 1580–1589 (1990).|
  26. Kahn, S. E., Bergman, R. N., Schwartz, M. W., Taborsky, G. J. & Porte, D. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans.  J. Physiol.1992;262: E518–E523.
  27. Ali M. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  28. Ali M, Braun EV, Fayemi AO:  Pathology.  7th ed.  New York, Med Exam, 1980,370 pp.
  29. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.Aging
  30. Ali M, Ramanarayanan MP, Nalebuff DJ, Fadal RG, Willoughby JW:  Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: effect of specific immunotherapy.  Am J Clin Pathol, 80:290-299, 1983.
  31. Ali M. Spontaneity of Oxidation in Nature and Aging,  (monograph). Teaneck, NJ, 1983.
  32. Ali M, Ramanarayanan MP:  A computerized micro-ELISA assay for allergen-specific IgE antibodies.  Am J Clin Pathol, 81:591-601, 1984.
  33. Ali M.   Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  34. Ali M. Altered States of Biology Ecology. (monograph). Teaneck, NJ, 1980.
  35. Murphy KG, Bloom SR. Gut hormones and the regulation of energy bhomeostasis. 2006;444:854-859.

  36. Ali M. Dysox Model of Cancer Cancer
  37. Philosophy and Science of holism in healing. APPNA Journal. 2015.
  38. Ali M. Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  39. Ali M. Molecular Basis of Autism and Dysuatonomia – The Impeded Progenitor Cell Progression (IPCP) model of ASD and Dysautonomia. Townsend Letterfor Doctors and Patients. 2017 (In press)
  40. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  41. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  42. Ali M. The Principles and Practice of Integrative Medicine Volume  XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press. 
  43. Insulin Laboratory Ranges. http://alidiabetes.org/2016/02/25/insulin-laboratory-ranges/
  44. Ali Importance of Subtyping Diabetes Type 2 Into Diabetes Type 2A and Diabetes Type 2B. Townsend Letter-The Examiner of Alternative Medicine. 2014; 369:56-58.
  45. Ali M. Dasoju S, Karim N, Amin J, Chaudary D. Study of Responses to Carbohydrates and Non-carbohydrate Challenges In Insulin-Based Care of Metabolic Disorders. Townsend Letter-The Examiner of Alternative Medicine. 2016; 391:48-51.
  46. Ali M. Integrative Cardiology and Chelation Therapies. The Principles and Practice of Integrative Medicine. Vol VI. . (2005) New York. Institute of Integrative Medicine Press.
  47. Fontoura P. Harnessing Emerging Science for Unmet Needs patient needs. In: Sponsor Feature. Nature. 2016;491, Preceding page S1.
  48. Wall DP, Esteban FJ, Deluca TF et al. Comparative analysis of neurological disorders focuses genome-wide search for autism genes. Genomics. 2008;93(2):120–9.

ALI GIO HEALING VIDEO LIBRARY

The left side panel of all parts of ALI GIO Healing presents in alphabetical order a large library of the author’s videos on diverse subjects covered in the series of articles. Two video links are included below as examples.

Redaers will find this series very informative an duseful.

END END

 


 

References

  1. Respiratory-to-Fermentative (RTF) Shift in ATP Production in Chronic Energy Deficit Disorders. Townsend Letter for Doctors and Patients. 2004;253:64-65.
  2. Ali M. Oxygen and Aging. Book Ali M. Oxygen and Aging. (Ist ed.) New York, Canary 21 Press. Aging Healthfully Book 2000. .
  3. Ali M. Succinate Retention. In: Chouchani ET, Victoria R. Pell VR, Edoardo Gaude E, et. al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature. 2014;515:431–435.
  4. Ali M. Succinate Retention: The Core Krebs Dysfunction in Immune-Inflammatory Disorders. Townsend Letter. 2015;388:84-85.
  5. Ali M: Darwin, oxidosis, dysoxygenosis, and integration. J Integrative Medicine 1999;3:11-16.
  6. Climatic Chaos –  The primacy of oxygen issues over carbon issues. Part I. Townsend Letter-The examiner of Alternative Medicine. 2008;299:125-132.
  7. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  8. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  9. Ali M. Epidemic of Dysoxygenosis and the Metabolic Syndrome. In: The Principles and Practice of Integrative Medicine. Volume 5. Pp 246-256. Canary 21 Press. New York. 2005.
  10. Ali M. Dysox Model of Diabetes and De-Diabetization Potential. Townsend Letter-The examiner of Alternative Medicine. 2007; 286:137-145.
  11. Ali Plan for Reversing Diabetes. New York, Canary 21 Press. Aging Healthfully Book 2011.
  12. Ali M. Oxygen, Insulin Toxicity, Inflammation, and  the Clinical Benefits of Chelation. Part I. Townsend Letter-The examiner of Alternative Medicine. 2009;315:105-109. October, 2009.
  13. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  14. Ali M. Insulin Reduction and EDTA Chelation: Two Potent and Complementary Approaches For Preventing and Reversing Coronary Disease. Oxygen, Insulin Toxicity, Inflammation, and the  Clinical Benefits of Chelation – Part II. Townsend Letter-The examiner of Alternative Medicine. 2010;323:74-79. June 2010. 
  15. Ali M. Fayemi AO, Ali O. Dasoju S, et al. Shifting Focus From Glycemic Status to Insulin Homeostasis. .  Townsend Letter-The Examiner of Alternative Medicine. 2017;402:91-96.
  16. Ali M. Oxidative Cell Membrane Disorder – Leaky Cell Membrane Disorder (monograph). Teaneck, NJ, 1987.
  17. Kahn SE, 1, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444, 840-846.
  18. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116 :1793B1801.
  19. Shulman G. Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease. N Engl J Med. 2014; 371:1131‑
  20. International Diabetes Federation. Diabetes Atlas. 2016. Seventh edition. diabetesatlas.org.
  21. Sako, Y. & Grill, V. E. A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation. Endocrinology127, 1580–1589 (1990).|
  22. Kahn, S. E., Bergman, R. N., Schwartz, M. W., Taborsky, G. J. & Porte, D. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans.  J. Physiol.1992;262: E518–E523.
  23. Ali M. Ali M. The Principles and Practice of Integrative Medicine Volume  III: Pathobiology by Micro-Ecologic Cellular and Macro-Ecologic Tissue-Organ Systems 1999.  New York. Canary 21 Press. 1999.
  24. Ali M, Braun EV, Fayemi AO:  Pathology.  7th ed.  New York, Med Exam, 1980,370 pp.
  25. Ali M. The dysox model of aging.  Townsend Letter for Doctors and Patients.2005;269:130-134.Aging
  26. Ali M, Ramanarayanan MP, Nalebuff DJ, Fadal RG, Willoughby JW:  Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: effect of specific immunotherapy.  Am J Clin Pathol, 80:290-299, 1983.
  27. Ali M. Spontaneity of Oxidation in Nature and Aging,  (monograph). Teaneck, NJ, 1983.
  28. Ali M, Ramanarayanan MP:  A computerized micro-ELISA assay for allergen-specific IgE antibodies.  Am J Clin Pathol, 81:591-601, 1984.
  29. Ali M.   Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  30. Ali M. Altered States of Biology Ecology. (monograph). Teaneck, NJ, 1980.
  31. Murphy KG, Bloom SR. Gut hormones and the regulation of energy bhomeostasis. 2006;444:854-859.

  32. Ali M. Dysox Model of Cancer Cancer
  33. Philosophy and Science of holism in healing. APPNA Journal. 2015.
  34. Ali M. Hyperinsulinism Associated With Breast and Prostate Cancer. Townsend Letter-The Examiner of Alternative Medicine.2017.
  35. Ali M. Molecular Basis of Autism and Dysuatonomia – The Impeded Progenitor Cell Progression (IPCP) model of ASD and Dysautonomia. Townsend Letterfor Doctors and Patients. 2017 (In press)
  36. Ali M. The Principles and Practice of Integrative Medicine Volume X: Darwin, Oxygen Homeostasis, and  Oxystatic Therapies.  3 rd. Edi. (2009) New York. Institute of Integrative Medicine Press.  
  37. Ali M. The Principles and Practice of Integrative Medicine Volume  XI: Darwin, Dysox, and Disease. 2000. 3rd. Edi. 2008. New York.  (2009) Institute of Integrative Medicine Press.  
  38. Ali M. The Principles and Practice of Integrative Medicine Volume  XII: Darwin, Dysox, and Integrative Protocols. New York (2009). Institute of Integrative Medicine Press. 
  39. Insulin Laboratory Ranges. http://alidiabetes.org/2016/02/25/insulin-laboratory-ranges/
  40. Ali Importance of Subtyping Diabetes Type 2 Into Diabetes Type 2A and Diabetes Type 2B. Townsend Letter-The Examiner of Alternative Medicine. 2014; 369:56-58.
  41. Ali M. Dasoju S, Karim N, Amin J, Chaudary D. Study of Responses to Carbohydrates and Non-carbohydrate Challenges In Insulin-Based Care of Metabolic Disorders. Townsend Letter-The Examiner of Alternative Medicine. 2016; 391:48-51.
  42. Ali M. Integrative Cardiology and Chelation Therapies. The Principles and Practice of Integrative Medicine. Vol VI. . (2005) New York. Institute of Integrative Medicine Press.
  43. Fontoura P. Harnessing Emerging Science for Unmet Needs patient needs. In: Sponsor Feature. Nature. 2016;491, Preceding page S1.
  44. Wall DP, Esteban FJ, Deluca TF et al. Comparative analysis of neurological disorders focuses genome-wide search for autism genes. Genomics. 2008;93(2):120–9.
  45. Wang K, Zhang H, Ma D, et al. Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature. 2009;459(7246):528–33.
  46. Ali alidiabetes.org . Inappropriate References ranges.
  47. Ali M. Integrative Cardiology and Chelation Therapies. The Principles and Practice of Integrative Medicine. Vol VI. . (2005) New York. Institute of Integrative Medicine Press.
  48. Ali M. Communication e-Published in Nature: Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome. Nature 534, 213 – 217 (7606) 
Published online: 2016-06-09; | doi:10.1038/nature18309.
  49. Ali M. Workable Simplicity for Coping With Complexity of the Metabolic Syndrome and Type 2 Diabetes. Commentary in: Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome. Nature 534, 213 – 217 (7606) 
Published online: 2016-06-09; | doi:10.1038/nature18309.
  50. Ali M. Hypothalamic Influences on Metabolism, Feeding, and Insulin Homeostasis. Commentary in: Stanley SA, Kelly L, Kaamashri N, et al. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature. 2016:531:647-650.
  51. Ali M. Oxygen and Aging. (Ist ed.) New York, Canary 21 Press. Aging Healthfully Book 2000. .
  52.  Ali M. Darwin, Oxygen Homeostasis, and  Oxystatic Therapies. The Principles and Practice of Integrative Medicine. Volume X. (2005) New York. Institute of Integrative Medicine Press.
  53.  Bourzac K. The First Step. Nature. 2012;491:S7-9.
  54.  Singer E. Redefining Autism. Nature. 2012;491:S12-13.
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