Statin Drugs Used To Prevent Heart Attacks Increase (38%) the risk of Diabetes, which Is A Recognized Major Risk Factor for Heart Attacks.
Majid Ali, M.D., F.R.C.S (Eng)
A Surgeon-Turned-Pathologist-Turned, Immunologist-Turned-Nutritionst-Turned-Clinical Ecologist-Turned-Integrationist
Solo Author, The Principles and Practice of Integrative Medicine
(in 12 volumes)
Solo Author, Dr. Ali’s Plan for Reversing Diabetes
Fellow of Royal College of Surgeons of England
Diplomate, American Board of Surgical Pathology
Diplomate, American Board of Clinical Pathology
Diplomate, American Board of Environmental Medicine
Diplomate, American Board of Chelation Therapy
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A recent study reported in the British Journal of Clinical Pharmacology (March 5, 2019) revealed that statin drugs used to lower blood cholesterol levels increase the risk of insulin resistance and high blood glucose levels by diabetes by 38 percent (ref. 1) This is not surprising for two reasons: (1) the findings are consistent with previous reports on the subject; and (2) in a 2017 report of 684 patients in the general population of New York metropolitan area, my colleagues published direct and incontrovertible evidence for the fact that raised levels of both the blood insulin and glucose levels directly lead to the development of diabetes (of Type 2, the main type of diabetes) (ref. 2) .
The study authors (ref. 2) recognized the following theoretical mechanisms which might underlie the link between statin drugs and increased risk of diabetes: (1) decreased insulin-mediated cellular glucose uptake (insulin resistance, in simply words) and (2) decreased
isoprenoid synthesis which causes downregulation of glucose transporter 4 and leads to hyperglycaemia and hyperinsulinemia, and (3) reduced factors such as coenzyme Q10, farnesyl pyrophosphate, and dolichol leading to altered insulin secretion/resistance.
References
- Ahmadizar F, OchoaRosales C, Glisic M, et al. Associations of statin use with glycaemic traits and incident type 2 diabetes. British Journal of Clinical Pharmacology. 05 March, 2019.
- Ali M. Fayemi AO, Ali Omar et al. Shifting Focus From Glycemic Status to Insulin Homeostasis for Stemming Global Tides of Hyperinsulinism and Type 2 Diabetes . Townsend Letter. January 2017.
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