What Is Optimal Insulin Homeostasis?

Majid Ali, M.D.

140 West End Avenue, New York, NY 10023




What Is Homeostasis?

Homeostasis is best considered a steady internal state of equilibrium in living beings – people, animals, and plants. It is created, preserved, and protected by a natural resistance of life forms to change in the optimal conditions.

I considered study of homeostasis of any element, substance (hormones, messengers, metabolites, etc.) as my top priority in all matters of health/diease/disease continuum. All homeostatic mechanisms have at least three central components which are exquisitely integrated and functionally for the specific factor (variable) being regulated: (1) a receptor; (2) a control centre; and (an effector).

The receptor is the sensing component that monitors and responds to changes in the environment, either external or internal. An effector is the target — a cellular population, a biologic system, or other discrete functions. An effector is the target acted on, to bring about the change back to the normal state.



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