Diabetes Is Not A Sugar Problem


Majid Ali, M.D.

140 West End Avenue, New York, NY 10023

212-873-2444

344 Prospect Avenue, Hackensack, NJ 07601

201-996-0027


 

Hyperinsulinism Predates Diagnosis of Diabetes by Five, Ten, or More Years. During these years, insulin toxicity remains unheeded and continually injures nearly all cell populations in the body. Most notably, it enlarges liver with fatty deposits (fatty disease of the liver) and shrinks the brain  by  decreasing blood and oxygen supply to the brain. 


Neglected and Improper Insulin Testing

The most disappointing aspect of the matter of insulin homeostasis in clinical practice is that, with very uncommon exceptions, hyperinsulinism is not detected with direct insulin testing. Insulin toxicity is allowed to inflict widespread cellular damage for years, sometimes for decades, until glycemic criteria for the diagnosis of Type 2 diabetes are met. This has been amply documented in this and past communications on the subject. Below are some specific issues concerning improper insulin testing;

  1. Insulin tests are performed on randomly drawn blood tests (Results of such tests  cannot be interpreted with confidence);

  2. Laboratories employ utterly unusable references ranges for blood insulin concentrations, as documented definitively in Table 1;

  3. Tests for glycemic status (fasting blood  glucose, two-hour postprandial glucose level, A1c levels) are performed as substitutes indicators of the insulin status;

  4. Cut-off points for post-glucose challenge blood insulin concentrations reported in laboratory reports are not based on actual post-glucose-challenge testing data; 39

  5. Gestational diabetes is a hyperinsulinism disorder before it becomes gestational diabetes by glycemic criteria;

  6. Pregnant women are unscientifically and improperly assured of their metabolic health simply because their glucose tolerance tests are considered negative for gestational diabetes;

  7. Insulin is the primary pro-weight gain and pro-obesity hormone, and yet insulin tests are not done in weight loss and obesity programs.

  8. Failure to assess insulin homeostasis with direct post-glucose challenge tests leaves patients and clinicians in the dark concerning the central roles of hyperinsulinism in the pathobiology of   chronic inflammatory, infectious, autoimmune, metabolic, neoplastic, and degenerative disorders.

Two important concerns in this context are: (1) Study of Responses to Carbohydrates and Non-carbohydrate Challenges In Insulin-Based Care of hyperinsulinism and related Metabolic Disorders40; and (2) Importance of Subtyping Diabetes Type 2 Into Diabetes Type 2A and Diabetes Type 2B.41

It is lamentable that in the dominant medical thought, crucial health and healing aspects of chronically sluggish oxygen signaling and incrementally exaggerated insulin signaling are consistently neglected. How often is the centrality of dysoxygenosis (dysfunctional oxygen signaling) in chronic diseases recognized and effectively addressed in doctors’ offices and clinics? How often are the fattening, fermenting, and inflaming effects of simmering hyperinsulinism detected and controlled by restoring optimal insulin metabolism? Mention of mitochondrial malfunctions evokes tired yawns; the word insulin triggers Pavlovian mumbling about diabetes.


 

 

 

 

Table 8. Insulin Reference Ranges in uIU/mL of Six Laboratories in New York Metropolitan Area15
Laboratory* Fasting 1-Hr 2-Hr  3-Hr
Laboratory 1 1.9 – 23 8 – 112 5 – 35 Not Reported
Laboratory 2 2.6 – 24.9 0.0 – 121.9 0.0 – 163.5 Not Reported
Laboratory 3 2.6 – 24.9 8 – 112 5 – 55 3 – 20
Laboratory 4 6 – 27 20 – 120 18 – 56 8 – 22
Laboratory 5 00 – 30 30 – 200 40 – 300 50 – 150
Laboratory 6 Does not include insulin ranges in the report. Instead it includes the following note: Insulin analogues may demonstrate non-linear cross-reactivity in this essay. Interpret results accordingly.**

*Upper and lower limits of laboratory reference ranges for blood insulin concentration determined following a Standard 75-gram glucose challenge.

**Personal communications with clinicians revealed that they do not find this laboratory note to be satisfactory in their clinical decision-making.

 

 


Ali Insulin Weight Loss PlanTM

7-C Insulin Weight Loss Diet PlanTM (“7-C Insulin Weight Plan”) was developed by team of scientists, including pathologists, immunologists, nutritionists, researchers in the fields of hyperinsulinism and insulin toxicity, metabolism, cellular energetics, and diseases of metabolism, including prediabetes, diabetes of various kinds, and clinical integrationists. A large library of published research papers is included in the citation section of this scholarly introduction to 7-C Insulin Plan.

7-C Weight Loss PlanTM has been clinically validated by a team of nutrition scientists, pathologists, basic science rsearchers, and clinical inttegrationistsresearches, pathologists, physicians, nm doctors, cWeight Lossas developed and clinically validated perfected TM Basic science research Pathologists Four decades Insulin is the fermenting.


 

Dr. Ali’s Protein-Lecithin Shake Breakfast

There is never a valid reason for missing breakfast. So strong is my conviction on the subjects of the need and the optimal type of breakfast that I seldom complete a visit with one of my patients without addressing it. Indeed, next to the subject of chronic anger I devote more time energy—and energy— to the matter of “Dr. Ali’s breakfast” than any other subject. In this chapter, I present information about what I consider to be a good breakfast and offer my reasons for my position on the subject.

Many patients tell me they missed their breakfast because they were not hungry. I explain that was so because their metabolic rhythm has been disrupted. Rising at 7 am following a dinner at 8 pm the evening before, of course, means a fasting of 11 hours. Fasting means hypoglycemia and acidosis. Extending that period for another two or three or more hours essentially sets a person up for major hypoglycemic-hyperglycemic shifts that trigger insulin and adrenergic roller coasters. In individuals with neurotransmitter volatility — persons with predisposition for anxiety, sadness, or depression — extension of fasting can trigger any or all of those symptoms. For others without such vulnerability, it is really a matter of time until they also succumb to undue tiredness or mood difficulties caused by glucose-insulin-adrenaline-neurotransmitter shifts.

Ali Insulin Weight Loss PlanTM

7-C Insulin Weight Loss Diet PlanTM (“7-C Insulin Weight Plan”) was developed by team of scientists, including pathologists, immunologists, nutritionists, researchers in the fields of hyperinsulinism and insulin toxicity, metabolism, cellular energetics, and diseases of metabolism, including prediabetes, diabetes of various kinds, and clinical integrationists. A large library of published research papers is included in the citation section of this scholarly introduction to 7-C Insulin Plan.

7-C Weight Loss PlanTM has been clinically validated by a team of nutrition scientists, pathologists, basic science rsearchers, and clinical inttegrationistsresearches, pathologists, physicians, nm doctors, cWeight Lossas developed and clinically validated perfected TM Basic science research Pathologists Four decades Insulin is the fermenting

 

Dr. Ali’s Insulin Weight Loss Diet and Detox Plan

Majid Ali, M.D.

 

 

 

Dr. Ali’s Protein Shake Breakfast

And Related Insulin-Smart Omelettes and Other Insulin-Smart Breakfasts for Insulin-Smart eating
There is never a valid reason for missing breakfast. So strong is my conviction on the subjects of the need and the optimal type of breakfast that I seldom complete a visit with one of my patients without addressing it. Indeed, next to the subject of chronic anger I devote more time energy—and energy— to the matter of “Dr. Ali’s breakfast” than any other subject. In this chapter, I present information about what I consider to be a good breakfast and offer my reasons for my position on the subject.

Many patients tell me they missed their breakfast because they were not hungry. I explain that was so because their metabolic rhythm has been disrupted. Rising at 7 am following a dinner at 8 pm the evening before, of course, means a fasting of 11 hours. Fasting means hypoglycemia and acidosis. Extending that period for another two or three or more hours essentially sets a person up for major hypoglycemic-hyperglycemic shifts that trigger insulin and adrenergic roller coasters. In individuals with neurotransmitter volatility — persons with predisposition for anxiety, sadness, or depression — extension of fasting can trigger any or all of those symptoms. For others without such vulnerability, it is really a matter of time until they also succumb to undue tiredness or mood difficulties caused by glucose-insulin-adrenaline-neurotransmitter shifts.

During the mid-1960s, as a house surgeon in Pakistan and later in England, I seldom ate a breakfast. I am not sure why that was so. Perhaps it was a macho thing — the real surgeons had to begin their mornings with something better than merely engaging Pakistani Praathas (heavily oiled and salted fried pita bread) or English porridge. More often than not, lunch was missed as well. By noon, I was nearly always in the midst of struggle with excising tissues soaked with bloody fluids. Sometimes there was a quick cup of coffee during the midday hours. At other times, I devoured a doughnut or a piece of pastry in the early afternoon hours. Now when I recall those days, I shudder to think who might have paid what price for the lack of any sense of nutrition — appalling ignorance, to be precise — of a driven, hypoglycemic, and inexperienced surgeon.

Dr. Ali’s Start-Low-Build-Slow Principle

In all guidelines for natural remedies for preserving health and reversing chronic diseases, I strongly advise readers to follow my Start-Low-Build-Slow Principle. Simply stated, this principle requires that an individual, in trying natural remedies, be cautious and closely observe how the body responds to natural remedies, beginning with small amounts or portions (as low as one-tenth the value on the first day, and doubling them every day until the recommended amount is reached.) If any negative senses are experienced, the item should be discontinued or taken in smaller amounts for longer periods of time to increase tolerance. It is important that a doctor be consulted to rule out the presence of serious coexisting or underlying conditions.
GOALS AND OBJECTIVES OF A GOOD BREAKFAST

A wholesome breakfast — in my view — should serve the following goals:

1. It should set the stage for an active, vigorous, and healthful day with sustained energy.
2. It should support the functions of the bowel, liver, hormone organs, brain, and other tissue.
3. It should sustain the long-term goals of healthful aging and preventing degeneratory disorders, such as heart disease, stroke, diabetes, Alzheimer’s disease, osteoporosis, and others.

With those goals in mind, the following objectives of a breakfast seem desirable to me:

1. Overhydration of cells throughout the body during the morning hours;
2. Maintenance of the blood glucose levels within a narrow healthful zone to avoid rapid hypoglycemic- hyperglycemic shifts, and to prevent insulin-adrenergic roller coasters initiated by those shifts;
3. Tonification of the bowel musculature and stimulation of the emptying reflexes;
4. Provision of special support for the hepatic redox-restorative detoxification pathways;
5. Provision of restorative oils for optimal biomembrane functions, especially in the brain;
6. Provision of raw material for structural and functional proteins, especially for generating oxystatic enzymes; and
7. Avoidance of toxic trans fatty acids, which are common in the standard American breakfasts.

Below, I describe my own breakfast, which seeks to meet the above goals and objectives of an optimal breakfast.

My Own Breakfast 3-4 Days a Week

I consider missing my breakfast a violation of the sacred temple that houses my spirit — an insult to my physical frame. I learned that crucial lesson the hard way. Earlier I referred to the absence of breakfast during my surgical days. That mistake was continued during two decades of my pathology work as well. My clinical experience and review of literature has convinced me that the single best:

1. That the premium nutrient for the brain is flaxseed oil;
2. That the single best nutrient for the liver is lecithin;
3. That the most desirable prescription for the integrity of bowel ecology is organic vegetable juice;
4. That the ideal formulation for the prevention of sugar-insulin-adrenaline roller coasters is a good protein powder, comprising 85 to 90% partially digested proteins; and
5. That the nutrient of choice for invigorating all the cells in the body is abundant water.

In view of those considerations, I prepare my own breakfast (within two to three minutes) on five or six days a week as follows:

1. I begin with a 28-ounce mug filled with spring water and one ounce of seltzer water (seltzer water is unnecessary for those who prefer plain water).
2. I drink the above-mentioned fluid volume in portions of five to seven ounces at intervals, doing limbic exercise — non-competitive exercise—between drinking. I take my probiotic protocol (Bifidobacterium and Acidophilus) when I begin to drink water.
3. I continue drinking that amount of water, taking additional supplements, until the mug is empty.
4. Next, I prepare a 30-ounce protein drink as shown in Table 1.
5. I begin drinking the above protein protocol, again consume five to seven ounces at a time, continuing my limbic exercise and taking additional supplements until both the complement of supplements and the protein formula is finished.
6. On weekends, my wife and I commonly take an egg breakfast with some fruit.

At the Institute, my colleagues and I use the following four P&P (partially digested protein) protocols: (1) #1 containing %90% mixture of proteins derived from eggs and milk; (2) # 2 containing 90% soy proteins; (3) # 3 containing 75 to 80 % rice protein; and (4) # 4 containing about 90% of whey protein. Proteins derived from other sources, such as vegetables, may be substituted for one or the other of the above choices. In Table 2, I make some recommendations for the choice of vegetables for preparing fresh juices:

The flaxseed oil in the protein drink may be replaced by one of the following oils: olive, safflower, sunflower, sesame, pumpkin, avocado, and almond. Additional comments on this subject are included in the next section.

I use the Very Veggie brand of bottled organic vegetable juice produced by Knudson Co. For those who can find the time, freshly squeezed vegetable juice is clearly preferable.

 

 

Table 1. Dr. Ali’s Breakfast
Five Days of the Weeks
Protein                                    Two heaping tablespoonsFlaxseed                                  Two heaping tablespoons

Lecithin (all natural)                   One heaping tablespoon

Vegetable juice, organic              15 ounces

Water                                      15 ounces

 

Insulin-Smart Omelettes and Other Insulin-Smart Breakfasts for Insulin-Smart eating
When we do what is right, habit makes it agreeable. That certainly is true of eating choices. Taste is an acquired faculty. Organic vegetable juice added to my protein drink now appeals to me much more than any fruit juice. It was not so when I began. (Fried brain is not a delicacy for me now as it once was in my childhood in Pakistan.) The habit one grows into for one’s breakfast is as much a part of the life’s track as any other. I explain those basic aspects of a wholesome breakfast to every patient who consults me.

Some patients readily follow my breakfast plan closely, begin to savor it soon, and report good results within weeks. Others take a slower approach, adopting my plan partially. Some patients initially find my prescription for breakfast unappetizing. The majority of them settle into them nicely weeks or months later. Yet others ask if they can replace organic vegetable juice with milk (cow’s, goats, rice or soy). Others wish to add one-half of a banana or peach or other types of fruit for enhanced taste. Except in patients with disturbing symptomatology related to rapid hypoglycemic-hyperglycemic shifts, I accept their modifications.

I do wholeheartedly endorse an egg breakfast. Eggs have been maligned for decades by practitioners of pharmacologic medicine on the grounds that eggs raise blood cholesterol levels. I dismiss that as non-sense coming from ill-informed individuals. Not a single study has shown that eggs increase the incidence of cardiovascular disease. Indeed, some reports suggest that eggs — an excellent source of high-quality liver-friendly lecithin —actually lower blood cholesterol levels.

Plain yogurt with freshly ground flaxseed makes for an excellent breakfast. Some fruit may be added to that for persons without immune disorders. Other good breakfast options are soy products commonly recommended by macrobiotic enthusiasts.

Oatmeal breakfast used to be a favorite of nutritionists of bygone eras. Nearly all nutritionists that I have discussed this subject with in recent years told me they now do not recommend oatmeal or any other starch breakfasts anymore. I believe that is because the abuse of antibiotics and massive sugar overload in the general public has so stressed the bowel ecosystem that even so-called healthy starches now carry the hazard of further feeding the sugar- eaters in the gut and so contribute to ongoing disruption of the bowel ecology.

In some cultures, fish, poultry, and various meats are consumed for breakfast. Those items are very desirable as sources of proteins. The important point here is that such meats should not be highly processed, nitrated, or otherwise contain high contents of oxidized fats.

 

Use Tabkes from the Turkish Patient Insulin graphs B(

To reverse pre-diabetes and diabetes (completely or partially), my primary objective is to lower both blood sugar and insulin levels by making insulin work better. For individuals with pre-diabetes with insulin toxicity but without high blood sugar levels, my goal is to lower blood insulin levels by increasing insulin efficiency.

Dr. Ali’s Insulin Reduction Protocol

My Insulin Reduction Protocol has two components:

  1. A plan of food choices to prevent sugar spikes that trigger insulin spikes, and
  2. A plan to do daily gentle bowel and liver detox.

In the Table 2 below, I present a case study to show how blood glucose and insulin levels were lowered (by increasing insulin efficiency) with the clinical application of Dr. Ali’s Insulin Reduction Protocol. I follow this with some explanatory comments. In Table 1, I present the insulin and glucose values of an individual in good metabolic health.

 

Table 1. Insulin-conserving Profile of a 77-Yr-Old Metabolically Fit 5′ 5″ Man Weighing 133 Lbs. He Was Seen for Allergy Treatment.
6.23. 2010 Fasting 1 Hr 2 Hr 3 Hr
Insulin <2 24 29 30
Glucose 78 96 75 71

 

Table 2. Concurrent Reduction of Blood Insulin and Blood Sugar Levels With Dr. Ali’s Insulin Reduction Protocol in a 58-Yr-Old Woman With Complete Loss of Hair (Alopecia), Chronic Fatigue, Memory Deficit, Underactive Thyroid Gland, Allergy, and Mood Swings.
10.28.10 Fasting 1 Hr 2 Hr 3 Hr
Insulin 9.7 184.4 35.3 24
Glucose 102 133 79 73
11.23.1202
Insulin 12.7 87.7 50.2
Glucose 96 117 77

Diabetes Reversal Requires a Philosophy of Healing

Diabetes Type 2 can be reversed neither with the denial of dieting nor with euphoria of eating. Diabetes can be reversed only with a philosophy of eating and living. It requires knowing the difference between being “diabetes-literate” and “healing-literate.” Diabetes is the number one cause of blindness, neuropathy, toe and limb amputations, kidney failure leading to dialysis, and increased risk of strokes, memory loss, and heart attacks. So reversing diabetes is an act of self-compassion. If these words pull you toward making an honest attempt to lose diabetes Type 2, please consider studying “Dr. Ali’s Course on Healing” (available at Error! Hyperlink reference not valid.

Five Important Facts About Insulin-Wise and Insulin-Unwise Foods

I coined the terms Insulin-Wise and Insulin-Unwise Foods to raise consciousness about the serious adverse effects of insulin spikes on all cell populations in the body.

  1. Insulin in excess (insulin toxicity) is fattening and inflaming.
  2. Healthy fats are insulin-friendly.
  3. Healthy proteins are insulin-friendly.
  4. All breads, pastas, fruits and fruit juices, and sugars are insulin-unfriendly.
  5. Vegetables are insulin-friendly.

Simply stated, Insulin-Wise foods facilitate insulin signals and other functions, while Insulin-Unwise foods impede or block insulin signals and other functions. I present this subject at length in my book entitled “Dr. Ali’s Plan for Reversing Diabetes” and in a 40-minute video seminar that can be downloaded from www.aliacademy.orgor by calling 1-800-633-6226.

Below are guidelines for Dr. Ali’s Insulin Diet. If initially this diet plan is found to be too hard and restrictive, one or two days a week may be taken as free days. Of course, some insulin benefits will be lost on such days.

Insulin-Friendly Breakfast for Saving Insulin and Preventing Diabetes

  1. Please consider “Dr. Ali’s Breakfast” (protein shake described below) four or five days a week.

2.` Take eggs and vegetables for breakfast the remaining two days.

  1. No fruit juices, breads, or toast.

Insulin-Friendly Lunch for Saving Insulin and Preventing Diabetes

  1. Large salad with goat cheese, chicken, or fish. All the olive or sesame oil you wish.
  2. Uncooked, steamed, or lightly stir-fried vegetables. All the olive or sesame oil you wish.

Mid-Afternoon Snack

Use four to six ounces of the Dr. Ali’s Breakfast shake (prepared in the morning and carried to work).

Insulin-Friendly Dinner for Saving Insulin and Preventing Diabetes

  1. All healthy fats and oils
  2. All healthy proteins
  3. Uncooked, steamed, or lightly stir-fried vegetables with melted butter or olive oil (to your heart’s content).

Optimal Breakfast Choices for Diabetes

Dr. Ali’s Breakfast on five to six days per week comprising: (1) two tablespoons of a protein powder containing 85 to 90 percent calories in proteins and peptides; (2) two tablespoons of a granular lecithin; (3) two tablespoons of freshly ground flaxseed (the use of a coffee grinder is recommended); (4) 12 to 16 ounces of organic vegetable juice (avoiding or minimizing the use of carrots and red beets); and (5) 12 to 16 ounces of water. A few ounces of seltzer water or a few drops of lemon juice may be added to suit personal taste. I personally consume this mixture in portions of six to eight ounces with my morning nutrient and herbal protocols during the period of my morning exercise, meditation, and preparation for work. I have not yet encountered any negative impact of the protein content in this breakfast on renal function. Still, individuals with serum creatinine levels above the normal range need to be monitored for renal function.

Insulin Channel on YouTube Science, Health, and Healing Encyclopedia

I offer about 75 videos on insulin in health and disease on my my YouTube Science, Health, and Healing Encyclopedia. I especially recommend the channel entitled “Seven Faces of Insulin Toxicity”: http://www.youtube.com/watch?v=zxtVhe0mnf4

Insulin – the Minister of Energy and Metabolism

I designate insulin to be the Minister of Energy and Metabolism to the Oxygen king of the human body. By its signals, it regulates the energy of all cells in the body. Of necessity, this means that insulin has a role to play in the health preservation of all such cells.

Insulin is a hormone produced in specialized cells of the pancreas gland called beta cells. It is a string made up of 51 amino acid molecules and has a molecular weight of 5808 Daltons. Insulin performs diverse metabolic and non-metabolic functions in the body. As for metabolism, its major functions include the transfer of glucose from the blood into the liver and muscle cells for storage and into the fatty tissues to stop the use of fat as fuel. Among the major non-metabolic functions are its roles in cellular development, differentiation, and death.

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