Oxygen, Cholesterol, and Lapdog Joes
New plaques in arteries rarely, if ever, show cholesterol crystals when examined under microscopes. In old and large plaques, cholesterol deposits are nearly always found in the deep regions, away from the plaque surface facing the flowing blood. These basic facts of pathology reveal that cholesterol is deposited after plaques have enlarged and caused deep tissue injury in the arterial wall. And yet, the public firmly believes that plaques are caused by cholesterol, and statin drugs are necessary to lower blood cholesterol levels (for decades, of course). How did people get so duped? For this, we can be grateful to journalistic lapdogs—“Lapdog Joes” seems to be a suitable designation for them—who are too lazy to dig out the facts of science themselves. They snooze in the laps of the useful idiots of statin makers and cherish their crumbs.
Cholesterol mediates cellular cross talk. Low blood cholesterol levels increase the risk of all brain disorders in which this association has been investigated. Natural, unrancid cholesterol is an antioxidant and anti-inflammatory substance of great importance in all considerations of health preservation and disease prevention. Oxygen keeps cholesterol in its natural and healthful form. Cholesterol turns rancid (oxidized) in states of dysfunctional oxygen metabolism (dysox). Lapdog Joes of the print and electronic news media have shown no interest in these basic facts of cholesterol science either. Why offend the all powerful statin makers?
The True Science Story of Plaques
The real culprits in the cause of heart attacks, strokes, and kidney failures are toxic acids, increased free radical activity, and synthetic chemicals. These elements damage blood components, making them sticky, initiating the formation of microclots and microplaques. Such clots and plaques, in turn, damage cells lining blood vessels called endo cells (endo is short for endothelial cells). This is the beginning of plaque formation. So, plaques in early stages are composed of dead and dying blood cells, dead and dying endo cells, and inflammatory cells. As they enlarge, they damage the connective tissue and the muscle cells in vessel walls. This is the true story of plaques in blood vessels which is well known to pathologists.
Healthy, unrancid cholesterol protects the endo cells and prevents heart attacks, strokes, and kidney failures. Lapdog Joes are not interested in this story either—and for the same reason. Cholesterol has but one molecular formula and one three-dimensional structure. If there is only one cholesterol, how does it become “good cholesterol” and “bad cholesterol”? Lapdog Joes are not curious about this. Cholesterol molecules wear garbs of different colors and shapes—carrying protein and cell membrane receptors in biology lingo—and so look different. The the real issue in the sordid cholesterol story is “the protein problem.” However, there are no drugs—read, profits—in correcting the protein problem, which can be addressed only by restoring oxygen’s detergent and signaling functions. Lapdog Joes would rather snooze in the laps of statin monsters than report on the protein problem.
“But don’t the foamy cells in vascular plaques contain cholesterol?” some drug doctors might challenge. Yes, they do, but essentially in the same proportion as in the blood. This brings us to another important story to which Lapdog Joes have been blind. No money here either. Consider this: The so-called “bad” LDL cholesterol, in reality, is a large complex of proteins and fats that also contains a small amount of cholesterol, which is neither good nor bad. It is just cholesterol. The LDL complex also contains proteins, polyunsaturated fatty acids, phospholipids, and antioxidants (beta carotene and vitamin E). Cholesterol represents a small portion of the complex. The makers of cholesterol drugs—Lipitor, Crestor, Zocor, Vytorin, and others—fiercely hide this information from the statin-eating public. Lapdog Joes are only too happy to comply.
On April 3, 2010, the Executive Director of Center for Science in Public Interest preached the cholesterol-statin scripture on C-Span for an hour. He told the viewers over and over that cholesterol clogs arteries. He didn’t mention statins because he knew no one in the U.S. can ever escape a cholesterol-statin commercial on TV on any given day. Long live lapdog Joes!
For further information on the subject, may I suggest my DVD entitled “Cholesterol,” and the following articles on the web:
1. Why Don’t Statin Drugs Work for Women?
2. Does Cholesterol Help the Elderly Live Longer?